11 Kidney Disease Prevention Habits That Protect Kidney Health

March 30, 2026

6. Protect kidneys from risky medicines and supplements

Photo Credit: Unsplash @Yarnit

Some common medications can harm kidneys when used long-term or in high doses. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen are frequent offenders. Use the lowest effective dose for the shortest time, and check with a clinician before taking them regularly. Also mention herbal supplements, over-the-counter remedies, and recent prescriptions to any provider; certain drug combinations can affect kidney function or interact with blood pressure and diabetes medicines. For chronic pain, ask about safer alternatives like topical therapies, physical therapy, or acetaminophen under guidance. The Cleveland Clinic and Doral Health & Wellness recommend routine medication reviews, especially for older adults and people with reduced kidney function. If you’re prescribed a new medicine, ask how often kidney function should be monitored. Stopping or changing medicines without medical advice can be risky, so work with your care team on safer options tailored to your needs.

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