11 Menopause Symptom Management Strategies That Ease the Transition

6. Non-hormonal prescription options: When medicines help

Several non-hormonal prescriptions can reduce hot flashes and mood symptoms when lifestyle measures aren’t enough. Antidepressants in the SSRI/SNRI classes often lower hot flash frequency and can help mood symptoms; gabapentin reduces nighttime hot flashes and improves sleep for some people; clonidine is another option for certain cases (Cleveland Clinic; Pharmacy Times). These medicines are prescribed based on individual symptoms and health history, and they carry possible side effects like nausea, fatigue, or blood pressure changes. Discuss potential benefits and risks with your clinician and consider starting with low doses under supervision. For women with specific risk factors, such as a history of breast cancer, non-hormonal options may be preferred. Quick safety note: Review drug interactions and side effects with your clinician and pharmacist before starting any new medication. Practical tip: Keep a symptom diary for two to four weeks to show your clinician the frequency and severity of hot flashes and mood changes; that helps choose the right prescription strategy.