11 Digestive Health Problems: Causes and Solutions Explained

February 28, 2026

6. Celiac Disease — Autoimmune Gluten Reaction

Celiac Disease — Autoimmune Gluten Reaction. Photo Credit: Getty Images @Yarnit

Celiac disease is an autoimmune condition where gluten damages the small intestine when someone eats wheat, barley, or rye. It affects around 1 in 100 people worldwide and can cause diarrhea, weight loss, fatigue, and nutrient deficiencies. The only proven treatment is a strict lifelong gluten-free diet. Testing should be done before starting a gluten-free diet because removing gluten first can give false-negative results. In households that prepare both gluten and gluten-free foods, cross-contamination is a frequent challenge; using separate utensils or designated preparation areas helps reduce accidental exposure. For people from South Asian backgrounds, traditional grain alternatives such as ragi, bajra, and jowar are useful options — but packaged foods must be checked for hidden gluten. Work with a dietitian experienced in celiac disease for safe meal planning and monitoring of nutrient intake.

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